GUWAHATI: Researchers at the Indian Institute of Technology Guwahati have developed novel and promising surface engineering approaches on the basis of bio-interfacial (protein-surface) interactions which can be potentially applied for the detection as well as prevention of SARS-CoV-2.
The novel coronavirus (SARS CoV-2) is composed of inner nucleic acid which is covered with surface spike glycoprotein. The interaction between the spike protein and contacting surfaces constitutes the key step of transmission of SARS CoV-2. Thus, the surface engineering, on one hand, shall facilitate a quick detection method of SARS CoV-2 and, on the other, it would be a very secure method of protection against SARS CoV-2, for example when applied on PPEs.
IIT Guwahati has been at the forefront in the fight against COVID-19 and has been contributing on many fronts through the research and developments for COVID-19 including a face shield, ventilator, disinfection chambers and tunnel, and testing kit under the able leadership of Prof. T.G. Sitharam, Director, IIT Guwahati.
The research team headed by Dr. Lalit M. Pandey, Associate Professor, Department of Biosciences and Bioengineering, IIT Guwahati, has made significant advancements on surface modifications and analysis of the bio-interfacial (protein-surface) interactions.
The studies have been published in reputed journals like Materials Science and Engineering C, Applied Surface Science, Langmuir, J. Phys. Chem. C and ACS Biomaterials Science & Engineering.